Promising Technology June 2010

Project #B-1375 carried out at the Belarusian State University was recently completed. As a result of the project, a new approach to audio indexation was developed. In order to provide an effective recognition, new algorithms were created. The new models provide high segmentation and classification scores for audio signals. Based on the proposed approach the algorithms for voice and language identification, music classification and recognition were developed and tested. This novel method could find applications in other fields such as biomedical signal processing tasks, especially for vocal cord pathology detection based on speech signals.

Through Project #3401, a complex nondestructive approach for the test of nanostructures, based on X-ray reflection and scattering analysis, was developed. The x-ray reflectometry method allows obtaining information about surface morphology and film-substrate including the structure of buried interfaces within a uniform cycle of measurements. High sensitivity of x-ray reflection spectroscopy of crystalline structure of synthesized films is very important for future development of nanoelectronics.

The leading institute on the project was the St Petersburg State University / Institute of Physics, with the assistance from VNIIEF as supporting institute and the Institute of Electronic Structure & Laser

The total budget for the project was $350,000 including $180,000 in research grants to scientists.

More technical information

Project #3737, carried out at the Engelhardt Institute of Molecular Biology (Moscow)came to completion. The research was aimed at the identification of diagnostic and prognostic markers of colon cancer – one of the most widespread and deadly of tumor types. The project resulted in the identification of three genes, whose synthesis is drastically reduced in more than 95% of patients already at early stages of the disease. Meticulous analysis of gene expression in hundreds of tumors (including surgical materials and biopsies collected during colonoscopy at Moscow Oncology Center) clearly demonstrated the diagnostic and prognostic value of gene expression monitoring, as well as its usefulness for selection of optimal treatment of patients and evaluation of possibility of metastasis.

The results of the work were described in three scientific papers and nine presentations at three international conferences. Two patents were filed in order to protect intellectual property rights. The project, which was completed in 36 months (total budget $330,000), has widespread clinical applications and obvious commercial value.

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