On October 28, 2004, the International Science and Technology Center celebrated its tenyear anniversary of operations with an all-day conference held in downtown Moscow.

The event brought together representatives from 13 Parties, representing 37 nations that are members of the ISTC; joining top-level representatives from government Ministries and legislative bodies, major scientific research centers, international organizations, and industrial concerns to reflect on ten years of successful ISTC activity and discuss the future development of the ISTC in a changing international context.

More than 300 top-level attendees at the anniversary conference listened to opening remarks from ISTC Party representatives, who noted that in a relatively short span of time the ISTC has emerged from a modest office with only a dozen staff members to its current day structure with a staff of 200 and branches in six countries, synchronizing the efforts of government structures, scientific institutions, and private businesses.

Distinguished government representatives joined global leaders in science and industry in panel discussions, devoted to examining the ISTC’s contribution to international nonproliferation programs, scientific innovation, and economic development. In the framework of science panel discussions the conference participants exchanged ideas on the ISTC's future role in the context of modern science and noted that having already proven itself as a successful international instrument for promoting and developing nonproliferation programs and international cooperative science, the ISTC is far from exhausting its potential.